NEOERIOCITRIN Chemical Properties

Melting point:

277°C

Boiling point:

960.7±65.0 °C(Predicted)

Density 

1.73±0.1 g/cm3 (20 ºC 760 Torr)

storage temp. 

Store at -20°C

solubility 

Soluble in methanol;

pka

7.14±0.40(Predicted)

form 

powder

color 

White

Water Solubility 

insoluble in water

BRN 

1696764

LogP

2.130 (est)

Safety Information

WGK Germany 

3

F 

10-21

HS Code 

29389090

MSDS

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NEOERIOCITRIN Usage And Synthesis

Chemical Properties

Off white powder

Uses

Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor[1][2].

Definition

ChEBI: A flavanone glycoside that is eriodictyol substituted by a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.

Biological Activity

Neoeriocitrin was one of several flavonoids th at completely blocked the okadaic acid-induced inhibition of autophagy in cultured mouse hepatocytes. It is suggested as tool in the study of intracellular protein phosphorylation and as a potential protectant against pathological hyperphosphorylations.

IC 50

AChE

References

[1] Li L, et al. Comparison of?neoeriocitrin?and naringin on proliferation and osteogenic differentiation in MC3T3-E1. Phytomedicine.?2011 Aug 15;18(11):985-9. DOI:10.1016/j.phymed.2011.03.002
[2] Liu C, et al. Extraction and Isolation of Acetylcholinesterase Inhibitors from Citrus limon Peel Using an in vitro Method. J Sep Sci.?2020 Jan 30. DOI:10.1002/jssc.201901252

NEOERIOCITRIN(13241-32-2)Related Product Information

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• NEOERIOCITRIN
• 4-ethoxypropiophenone