Gantenerumab
Gantenerumab Basic information
- Product Name:
- Gantenerumab
- Synonyms:
-
- Gantenerumab
- Research Grade Gantenerumab(DHC12503)
- Gantenerumab (anti-Amyloid Beta)
- Research Grade Gantenerumab
- CAS:
- 1043556-46-2
- MW:
- 0
- Mol File:
- Mol File
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Gantenerumab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Gantenerumab Usage And Synthesis
Uses
Gantenerumab is a monoclonal antibody for the treatment of Alzheimer's disease being developed by Hoffmann-La Roche pharmaceuticals.
in vivo
Gantenerumab (20 mg/kg; intravenous injection; once a week; 5 months) has a protective effect in PS2APP transgenic mice and can reduce the number of Aβ amyloid plaques[1].
| Animal Model: | PS2APP transgenic mice by administering a single anti-CD4 injection[1] |
| Dosage: | 20 mg/kg |
| Administration: | Intravenous injection; once a week; 5 months |
| Result: | Reduced the number of Aβ amyloid plaques in PS2APP mice compared with vehicle controls. Specifically, in the hippocampus, neocortex, and thalamus, the plaque numbers were significantly reduced by 36%, 40%, and 70% respectively. Efficiently reduced the number of smaller plaques. Did not cause neurological or locomotor deficits. |
GantenerumabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Guangzhou Hongyuan Chemical Co.,Ltd
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- 15817493340
- 981810490@qq.com
Wuhan Chemstan Biotechnology Co., Ltd.
- Tel
- 027-65317797 15926423062
- 422450190@qq.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com
Biolab Reagents
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- 027-65279366 18108604356
- products@biolabreagent.com