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Dolutegravir Impurity 8
Dolutegravir Impurity 8 Basic information
- Product Name:
- Dolutegravir Impurity 8
- Synonyms:
-
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
- Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity)
- 2,6-Di fluoro Dolutegravir
- 2,6 Difluoro dolutegravir sodium salt
- 4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir
- (4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- Dolutegravir 2,6-difluoro Impurity
- Dolutegravir Impurity 59
- CAS:
- 2244161-72-4
- MF:
- C20H19F2N3O5
- MW:
- 419.38
- Mol File:
- 2244161-72-4.mol
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Dolutegravir Impurity 8 Chemical Properties
- Boiling point:
- 664.9±55.0 °C(Predicted)
- Density
- 1.53±0.1 g/cm3(Predicted)
- pka
- 4.50±1.00(Predicted)
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Dolutegravir Impurity 8 Usage And Synthesis
Uses
4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir Impurity 8Supplier
Shenzhen Roark Pharma-Tec Co., Ltd. Gold
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Shanghai Kewel Chemical Co., Ltd.
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Hubei Yangxin Medical Technology Co., Ltd.
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CR Corporation Limited
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Dolutegravir Impurity 8(2244161-72-4)Related Product Information
- Dolutegravir Impurity 18
- Dolutegravir Impurity C
- Dolutegravir Impurity 19
- Dolutegravir Impurity 7
- Dolutegravir SR Isomer
- Dolutegravir Impurity 21
- Dolutegravir Impurity 8
- Dolutegravir Impurity 13(Sodium Salt)
- Dolutegravir Impurity 6
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- Dolutegravir Glucuronide
- Dolutegravir Impurity 22
- Dolutegravir Impurity 14(Sodium Salt)
- Dolutegravir Glucoside
- Duluvir impurity 1
- Dolutegravir Impurity 24