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6-Chloro-2,3-diaminotoluene

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6-Chloro-2,3-diaminotoluene Basic information

Product Name:
6-Chloro-2,3-diaminotoluene
Synonyms:
  • 6-CHLORO-2,3-DIAMINOTOLUENE
  • 4-Chloro-3-Methylbenzene-1,2-diaMine
  • 1,2-Benzenediamine, 4-chloro-3-methyl-
  • Phloroglucinol Impurity 241
CAS:
673487-36-0
MF:
C7H9ClN2
MW:
156.61
Mol File:
673487-36-0.mol
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6-Chloro-2,3-diaminotoluene Chemical Properties

Melting point:
46-47 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling point:
305.6±37.0 °C(Predicted)
Density 
1.281±0.06 g/cm3(Predicted)
pka
3.65±0.10(Predicted)
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6-Chloro-2,3-diaminotoluene Usage And Synthesis

Uses

6-Chloro-2,3-diaminotoluene is a white solid powder at room temperature and pressure, with significant alkalinity and strong nucleophilicity. Due to the presence of two amino units in the ortho position of the benzene ring, it can undergo condensation reactions with aldehydes to prepare corresponding benzimidazole derivatives. This reaction is widely used to prepare benzimidazole drugs and bioactive molecules. It is an intermediate in organic synthesis and medicinal chemistry, such as Nemonapride.

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