NF 157 Chemical Properties

storage temp. 

Desiccate at RT

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Powder

Water Solubility 

Soluble to 50 mM in water

Stability:

Hygroscopic

NF 157 Usage And Synthesis

Uses

NF 157 is an inhibitor of the P2Y11 receptor.

Biological Activity

Purinergic receptor antagonist that potently inhibits P2Y 11 receptor activity (IC 50 = 463 nM). Displays selectivity for P2Y 11 and P2X 1 receptors over P2Y 1 , P2Y 2 , P2X 2 , P2X 3 , P2X 4 and P2X 7 receptors. Inhibits NAD + -induced activation of human granulocytes.

storage

Desiccate at RT

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