1-Cyanotetraline Chemical Properties

Melting point:

48-50 °C

Boiling point:

309 °C

Density 

1.06

refractive index 

1.55

Flash point:

114 °C

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly)

form 

Oil

color 

Colourless to Yellow

InChI

InChI=1S/C11H11N/c12-8-10-6-3-5-9-4-1-2-7-11(9)10/h1-2,4,7,10H,3,5-6H2

InChIKey

HMRIXHRQNXHLSL-UHFFFAOYSA-N

SMILES

C1(C#N)C2=C(C=CC=C2)CCC1

Safety Information

HS Code 

2926907090

1-Cyanotetraline Usage And Synthesis

Chemical Properties

light yellow oil liquid

Uses

1-Cyanotetraline is used in the synthesis of aldose reductase inhibitors. Also reductase enzymes are believed to catalyze the formation of sorbitol from glucose leading to the chronic complications of diabetes mellitus. It is also used in the synthesis of baclofen analogs, potent GABAB agonists.

Synthesis Reference(s)

Journal of the American Chemical Society, 99, p. 959, 1977 DOI: 10.1021/ja00445a057
Tetrahedron Letters, 36, p. 4307, 1995 DOI: 10.1016/0040-4039(95)00746-Y

1-Cyanotetraline(56536-96-0)Related Product Information

• Sodium hydride
• Decahydronaphthalene
• 1,2,3,4-Tetrahydronaphthalene
• Sodium cyanoborohydride
• Ethyl N-cyanoethanimideate
• ETHYL 2-CYANOACRYLATE
• Pyrrolidine
• Hydrogenated Vegetable Oil
• 2-Mercapto-5-methyl-1,3,4-thiadiazole
• 7-Fluoroisatin
• Methylene dithiocyanate
• 1-Cyanotetraline
• 1-amino-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carbonitrile
• 1-amino-1,2,3,4-tetrahydronaphthalene-1-carbonitrile
• 1-piperazin-1-yl-1,2,3,4-tetrahydronaphthalene-1-carbonitrile
• 5-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALENE-1-CARBONITRILE
• Cyano
• Tetrahydro