2-Chloro-4-hydroxybenzoic acid Chemical Properties

Melting point:

207-209 °C

Boiling point:

349.6±27.0 °C(Predicted)

Density 

1.536±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

pka

3.44±0.25(Predicted)

form 

Crystalline Powder

color 

Off-white to beige or orange-brown

CAS DataBase Reference

56363-84-9(CAS DataBase Reference)

EPA Substance Registry System

Benzoic acid, 2-chloro-4-hydroxy- (56363-84-9)

Safety Information

Risk Statements 

41

Safety Statements 

24/25-39-26

HS Code 

29189900

MSDS

• Language:English Provider:2-Chloro-4-hydroxybenzoic acid
• Language:English Provider:ACROS

2-Chloro-4-hydroxybenzoic acid Usage And Synthesis

Application

2-Chloro-4-hydroxybenzoic acid contains a carboxyl unit and a phenolic hydroxyl group in its chemical structure, exhibiting strong acidity. Literature reports that this carboxyl group and phenolic hydroxyl unit can undergo nucleophilic substitution reactions with iodomethane compounds under alkaline conditions, as well as esterification and etherification reactions. 2-Chloro-4-hydroxybenzoic acid is mainly used as an intermediate in organic synthesis and a basic reagent in pharmaceutical chemistry. Due to the chemical transformation activity of the carboxyl unit and phenolic hydroxyl group, some literature reports that this substance can be used for the structural modification and synthesis of antidiuretic hormone.

Chemical Properties

off-white to beige or orange-brown cryst. powder

2-Chloro-4-hydroxybenzoic acid(56363-84-9)Related Product Information

• Salicylic acid
• 3-Chloroperoxybenzoic acid
• Butylparaben
• 4-Hydroxybenzoic acid
• Isopropylparaben
• Methylparaben
• 2'-Hydroxy-3-phenylpropiophenone
• 3-Hydroxybenzoic acid
• Difluorochloromethane
• 3-CHLORO-4-HYDROXYBENZOIC ACID
• 2-Chloro-4-methoxybenzoic acid
• 3,5-Dichlorosalicylic acid
• ETHYL 2-CHLORO-6-HYDROXYBENZOATE
• ETHYL 3,5-DICHLORO-4-HYDROXYBENZOATE
• 4-CHLORO-2-HYDROXYBENZOIC ACID,4-Chlorosalicylic Acid/4-Chloro-2-hydroxybenzoic acid,4-Chloro-2-hydroxybenzoic acid 95%
• 3-CHLORO-4-HYDROXYBENZOIC ACID METHYL ESTER,3-CHLORO-4-HYDROXYBENZOIC ACID METHYL ESTER 97%
• 4-CHLORO-3-HYDROXYBENZOIC ACID ---PURITY 98%---,4-CHLORO-3-HYDROXYBENZOIC ACID
• 2-CHLORO-5-HYDROXYBENZOIC ACID