2,5-Dichlorophenol Chemical Properties

Melting point:

54-57 °C (lit.)

Boiling point:

211 °C (lit.)

Density 

1.3446 (rough estimate)

refractive index 

1.4430 (estimate)

Flash point:

100 °C

storage temp. 

0-6°C

solubility 

2000mg/l (experimental)

form 

Crystals

pka

7.53±0.10(Predicted)

color 

White to light brown

Water Solubility 

3 g/L (20 ºC)

BRN 

1907692

LogP

3.06 at 20℃

CAS DataBase Reference

583-78-8(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 2,5-dichloro-(583-78-8)

EPA Substance Registry System

2,5-Dichlorophenol (583-78-8)

Safety Information

Hazard Codes 

C,N,Xn

Risk Statements 

22-34-51/53-36/38

Safety Statements 

26-36/37/39-45-61-37/39

RIDADR 

UN 2020 6.1/PG 3

WGK Germany 

2

RTECS 

SK8600000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29081000

Hazardous Substances Data

583-78-8(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 580 mg/kg

MSDS

• Language:English Provider:2,5-Dichlorophenol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,5-Dichlorophenol Usage And Synthesis

Chemical Properties

white to light brown crystals

Uses

2,5-Dichlorophenol may be used as an analytical reference standard for the determination of the analyte in water, and wood, paper, cardboard, fruits, and fruit juices using simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography-electron-capture detection (GC-ECD) and gas chromatography-mass spectrometry (GC-MS), respectively.

Uses

2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.

Definition

ChEBI: A dichlorophenol with the chloro substituents at positions 2 and 5.

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052

General Description

Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 μg/L at 68-72°F; 33 μg/L at 86°F. Taste threshold 0.5 μg/L.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,5-Dichlorophenol are not available. 2,5-Dichlorophenol is probably combustible.

Purification Methods

Crystallise it from ligroin and sublime it in a vacuum or distil it. [Beilstein 6 IV 942.]

2,5-Dichlorophenol(583-78-8)Related Product Information

• Thionyl chloride
• Dichloroethane
• 1,2-Dichloroethane
• Sodium dichloroisocyanurate
• N,N-Dimethylacetamide
• Quinclorac
• 2-Phenylphenol
• 2',4'-Dichloroacetophenone
• 2,4,5-Trichlorophenol
• 2,4,5-Trichlorophenoxyacetic acid
• Hexachlorophene
• 2,3,5,6-TETRACHLOROANISOLE
• 2,3,6-TRICHLOROPHENOL
• TETRACHLOROCATECHOL
• 2,3-DICHLOROPHENOL 99+%
• 2,4-DICHLOROPHENOL pract,2,4-DICHLOROPHENOL 99+%
• 2,6-DICHLOROPHENOL extrapure
• 3,5-DICHLOROPHENOL TYPICALLY 99%