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Pyridoxine hydrochloride

Basic information Nutrition supplements Safety Supplier Related

Pyridoxine hydrochloride Basic information

Product Name:
Pyridoxine hydrochloride
Synonyms:
  • campoviton6
  • hexabetalin
  • hexa-betalin(r)
  • hexabionehydrochloride
  • hexavibex
  • hexermin
  • hexobion
  • paxadon
CAS:
58-56-0
MF:
C8H12ClNO3
MW:
205.64
EINECS:
200-386-2
Product Categories:
  • Inhibitors
  • Vitamin Ingredients
  • Nutritional Supplements
  • Vitamins and derivatives
  • Aromatics
  • vitamin
  • Biochemistry
  • Pyridinium Compounds
  • Vitamins
  • Heterocycles
  • Vitamin series
  • Isolabel
Mol File:
58-56-0.mol
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Pyridoxine hydrochloride Chemical Properties

Melting point:
214-215 °C(lit.)
Density 
1.2784 (rough estimate)
vapor density 
7.1 (vs air)
refractive index 
1.5800 (estimate)
Flash point:
9℃
storage temp. 
room temp
solubility 
H2O: 0.1 g/mL at 20 °C, clear, colorless
form 
Crystalline Powder
color 
White to almost white
PH Range
3.2
Water Solubility 
0.1 g/mL (20 ºC)
Sensitive 
Light Sensitive
Merck 
14,7982
BRN 
3632435
Stability:
Stable. Protect from air and light.
CAS DataBase Reference
58-56-0(CAS DataBase Reference)
EPA Substance Registry System
5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride (58-56-0)
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Safety Information

Hazard Codes 
Xi,T,F
Risk Statements 
36/37/38-39/23/24/25-23/24/25-11
Safety Statements 
26-37/39-45-36/37-16-7-24/25
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
2
RTECS 
UV1350000
8-10
TSCA 
Yes
HS Code 
29362500
Hazardous Substances Data
58-56-0(Hazardous Substances Data)
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Pyridoxine hydrochloride Usage And Synthesis

Nutrition supplements

Pyridoxine hydrochloride is the hydrochloride salt of Vitamin B6. Vitamin B6 (B6) is a water-soluble vitamin, which can be found in various foods such as fish, poultry, whole grains, legumes, banana, nuts, and sesame.Vitamin B6 has an important role in the metabolism of amino acids as a coenzyme, pyridoxal 5'-phosphate. 
B6 may exert an anticolon tumor effect by the protection of the colon epithelium from damage in rats treated with 1,2-dimethylhidrazine (DMH) and to decreased lithocholic acid, a colon carcinogen. Vitamin B6 may prevent such diseases by lowering inflammation. 

Chemical Properties

White or almost white, crystalline powder.

Uses

One of the vitamins of the B6 complex; present in many foodstuffs (yeast, liver and cereals). It has a role in transporting protein Bsu1, contributes to thiamine uptake; characterization of thiamine (vitamin B1) transporter Thi9 from Schizosaccharomyces p

Uses

Pyridoxine is one of the vitamins of the B6 complex; present in many foodstuffs (yeast, liver and cereals). Pyridoxine has a role in transporting protein Bsu1, Pyridoxine contributes to thiamine uptak e; characterization of thiamine (vitamin B1) transporter Thi9 from Schizosaccharomyces pombe.

Uses

Pyridoxine Hydrochloride is an acid form of vitamin b6, a water- soluble vitamin. it is soluble in water, and slightly soluble in alco- hol. it is slowly affected by sunlight and is reasonably stable in air. it has a ph of 2.3–3.5. it is also termed vitamin b6 hydrochloride. see pyridoxine.

Definition

An aldehyde derivative of pyridoxine, with vitamin B6activity,

brand name

Hexa-Betalin (Lilly).

General Description

Vitamin B6 has six forms namely, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Pyridoxine is a is a water-soluble vitamin and a pyrimidine derivative of vitamin B6. It is considered heat and acid stable.

Biochem/physiol Actions

Vitamin B6 is an essential coenzyme for amino acid, carbohydrate and lipid metabolism. Pyridoxine serves as a primary source in multivitamins. Pyridoxine deficiency is associated with peripheral neuropathy.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion, intramuscular, and subcutaneous routes. Human reproductive effects by ingestion and intramuscular routes: postpartum changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Purification Methods

Purify the vitamin by recrystallisation from EtOH/Me2CO, n-BuOH or MeOH/Et2O. Its solubility in H2O is 22%, and in EtOH it is 1.1%. It is insoluble in Et2O and CHCl3. Acidic aqueous solutions are stable at 120o/30minute. The free base has m 159-160o after recrystallisation from Me2CO and sublimation at 140-145o/0.0001mm. It has UV max at 290nm ( 84,000), 253 and 325nm ( 3,700 and 7,100) in 0.1N aqueous HCl. [Khua & Wendt Chem Ber 71 780 1938, 72 311 1939, Harris & Folkers J Am Chem Soc 61 1242 1939, Harris et al. J Am Chem Soc 62 3198 1940, Beilstein 21/5 V 492.]

Pyridoxine hydrochloride Preparation Products And Raw materials

Preparation Products

Raw materials

Pyridoxine hydrochlorideSupplier

Nanjing Jinhao Pharmaceutical Co., Ltd. Gold
Tel
13382796873;13376086365;15851804510
Email
hjz8008@163.com
Wuhan Huajiu Pharmaceutical Technology Co.,Ltd. Gold
Tel
027-59225746-
Email
730880265@qq.com
Tianjin Zhongxin Chemtech Co., Ltd.
Tel
022-66880623;022-89880623
Email
sales@tjzxchem.com;sales@tjzxchem.com
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Email
sh@meryer.com