Isobutyryl chloride Chemical Properties

Melting point:

-90 °C (lit.)

Boiling point:

91-93 °C (lit.)

Density 

1.017 g/mL at 25 °C (lit.)

vapor pressure 

0.07 mm Hg ( 20 °C)

refractive index 

n20/D 1.407(lit.)

Flash point:

34 °F

storage temp. 

Store below +30°C.

solubility 

Miscible with chloroform, glacial acetic acid, ether, toluene, methylene chloride and benzene.

form 

Liquid

color 

Clear

Odor

Stench

PH

<7 (H2O)

explosive limit

2.1-8.2%(V)

Water Solubility 

Reacts

Sensitive 

Moisture Sensitive

BRN 

605393

CAS DataBase Reference

79-30-1(CAS DataBase Reference)

NIST Chemistry Reference

2-Methylpropanoyl chloride(79-30-1)

EPA Substance Registry System

Propanoyl chloride, 2-methyl- (79-30-1)

Safety Information

Hazard Codes 

F,C,T

Risk Statements 

11-35-23

Safety Statements 

16-23-26-36-45-36/37/39-28A

RIDADR 

UN 2395 3/PG 2

WGK Germany 

1

RTECS 

UC3944000

F 

13

Autoignition Temperature

325 °C

Hazard Note 

Highly Flammable/Corrosive/Moisture Sensitive

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29147090

HS Code 

29159080

MSDS

• Language:English Provider:2-Methylpropanoyl chloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Isobutyryl chloride Usage And Synthesis

Chemical Properties

Colorless liquid.Soluble in ether; reacts with water and alcohol.

Uses

Usually used in the synthesis of fully isobutyramide terminated hyperbranched polyethylenimines,the separation and identification of shikonin and its ester derivatives in the root epidermis of Echium italicum.

Uses

Isobutyryl chloride is used in the preparation of fully isobutyramide terminated hyperbranched polyethylenimines. It plays an important role in the separation and identification of shikonin and its ester derivatives in the root epidermis of Echium italicum L. It acts as an acylating agent for the ketimine derivatives of alfa-amino esters, nucleosides and pyrroles. Further, it is used in the preparation of organic peroxides. In addition to this, it is used as an intermediate for dyes, textile auxiliaries and peroxide compounds.

General Description

A colorless liquid. Flash point near 50°F. Irritates skin, eyes and mucous membranes. Toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Produces corrosive toxic fumes containing HCl on contact with moist air. Decomposes in water.

Reactivity Profile

Isobutyryl chloride is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Low toxicity by inhalation. A severe eye irritant.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Flammability and Explosibility

Highly flammable

Isobutyryl chloride(79-30-1)Related Product Information

• Chloroacetyl chloride
• Choline chloride
• Oxalyl chloride
• Calcium chloride
• Polyvinyl chloride
• Sulfuryl chloride
• Isobutyrophenone
• Ammonium chloride
• Butyryl chloride
• Isobutyramide
• Mepiquat chloride
• 3,5,5-Trimethylhexanoyl chloride
• Acryloyl chloride
• Sodium chloride
• Benzyl chloride
• Benzoyl chloride
• Potassium chloride
• Methyl isobutyrylacetate