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N,N-Dimethyl-L-proline

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N,N-Dimethyl-L-proline Basic information

Product Name:
N,N-Dimethyl-L-proline
Synonyms:
  • (2s)-1,1-dimethylpyrrolidinium-2-carboxylate
  • (Pyrrolidinium, 2-carboxy-1,1-dimethyl-, innersalt, (2S)-
  • Methyl hygrate betaine
  • (S)-2-Carboxy-1,1-dimethylpyrrolidinium hydroxide inner salt
  • 1-Methylproline methylbetaine
  • Cadabine
  • (2S)-1,1-Dimethyl-2-carboxylatopyrrolidin-1-ium
  • (2S)-2-Carboxylato-1,1-dimethylpyrrolidin-1-ium
CAS:
471-87-4
MF:
C7H14NO2
MW:
144.19
EINECS:
207-445-1
Product Categories:
  • Alkaloids
  • Natural Plant Extract
Mol File:
471-87-4.mol
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N,N-Dimethyl-L-proline Chemical Properties

Melting point:
235°C
Boiling point:
261.28°C (rough estimate)
Density 
1.1095 (rough estimate)
refractive index 
1.4150 (estimate)
storage temp. 
2-8°C
solubility 
Water: 100 mg/mL (698.42 mM); DMSO: 100 mg/mL (698.42 mM)
form 
Solid
color 
White to off-white
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Safety Information

HS Code 
29214980

MSDS

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N,N-Dimethyl-L-proline Usage And Synthesis

Description

This alkaloid, which has been isolated from the leaves of Cadaba fruticosa, has been shown, by comparison of its hydrochloride and the NMR spectrum, to be stachydrine.

Uses

Stachydrine is used for various ethnobotany and ethnomedicinal uses. It can also be used to promote healthy neural development in an unborn baby, as well as to determine the differential effects of post-weaning diet and maternal obesity on mouse liver and brain metabolomes.

Definition

ChEBI: L-proline betaine is an amino acid betaine that is L-proline zwitterion in which both of the hydrogens attached to the nitrogen are replaced by methyl groups. It has a role as a food component, a plant metabolite and a human blood serum metabolite. It is a N-methyl-L-alpha-amino acid, an alkaloid and an amino-acid betaine. It is functionally related to a L-prolinium. It is a conjugate base of a N,N-dimethyl-L-prolinium. It is an enantiomer of a D-proline betaine.

References

Ahmad, Basha, Atta-ur-Rahman, Pak. J. Sci. Ind. Res., 17, 109 (1975)

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