Cuscohygrine Chemical Properties

Melting point:

（152（14 mmHg））

Boiling point:

bp23 169-170°; bp14 152°; bp2 118-125°

Density 

d420 0.9733

refractive index 

nD20 1.4832

storage temp. 

-20°C Freezer

solubility 

Chloroform (Soluble), Ethyl Acetate, Methanol (Slightly)

form 

Oil

color 

Clear Colourless to Light Yellow

Stability:

Solutions are unstable.

Cuscohygrine Usage And Synthesis

Chemical Properties

Clear Colourless Oil

Uses

It was the main alkaloid found in medicinal plants Datura metel.

Definition

ChEBI: Cuscohygrine is a N-alkylpyrrolidine and a pyrrolidine alkaloid.

Synthesis

When 1-methyl-2-tetrahydropyrrolidone was used as the raw material for the synthesis of red crotonine, a small amount of unreacted raw material existed due to the control of reaction conditions during the synthesis process, which affected the product quality. In order to separate them, we found the appropriate thin-layer chromatographic conditions after several tests, and the separation of the chromatographic spots obtained more satisfactory results. Atropine workshop to extract tropine alkaloids left mother liquor, separation of hydrobromide to obtain the red crocodiline, the latter's aqueous solution by ammonia, chloroform extraction, drying, remove chloroform, distillation under pressure, that is, to obtain the red crocodiline: boiling point, 178 a 179.

Cuscohygrine(454-14-8)Related Product Information

• ALOPERINE
• N-Methyl-2-pyrrolidone
• Propane
• 1-Methylpyrrolidine
• (-)-LUPININE
• Nortropine
• 8-METHYL-8-AZABICYCLO[3.2.1]OCTANE
• Pseudotropine
• Tropic acid
• Tropine
• Atropine
• STRYCHNINE
• Arecoline hydrobromide
• MONOCROTALINE
• ANISODINE
• METHYL-2-PYRROLIDONE
• Cuscohygrine
• AKOS 237-74