Doxefazepam Chemical Properties

Melting point:

138-140°

Boiling point:

204.52°C (rough estimate)

Density 

1.3534 (estimate)

storage temp. 

Store at -20°C

pka

11.55±0.40(Predicted)

form 

Solid

color 

White to off-white

InChI

InChI=1S/C17H14ClFN2O3/c18-10-5-6-14-12(9-10)15(11-3-1-2-4-13(11)19)20-16(23)17(24)21(14)7-8-22/h1-6,9,16,22-23H,7-8H2

InChIKey

VOJLELRQLPENHL-UHFFFAOYSA-N

SMILES

N1(CCO)C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=NC(O)C1=O

IARC

3 (Vol. 66) 1996

Safety Information

RIDADR 

3249

HazardClass 

6.1(b)

PackingGroup 

III

Toxicity

LD50 in rats, mice (mg/kg): 2550, >1500 orally; 586, 774 i.p. (Babbini)

Doxefazepam Usage And Synthesis

Description

Doxefazepam is a benzodiazepine hypnotic somewhat more potent than flurazepam.

Originator

Schiapparelli (Italy)

Definition

ChEBI: Doxefazepam is a benzodiazepine.

brand name

DOXANS

Doxefazepam(40762-15-0)Related Product Information

• 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo-1,4-diazepin-2-one monohydrochloride
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• Doxefazepam
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• OXAZEPAM
• TEMAZEPAM
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