17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Chemical Properties

Melting point:

209-212 °C(Solv: acetone (67-64-1); hexane (110-54-3))

Boiling point:

548.3±50.0 °C(Predicted)

Density 

1.24±0.1 g/cm3(Predicted)

solubility 

Acetone (Slightly), Chloroform (Slightly)

form 

Solid

pka

12.53±0.70(Predicted)

color 

White to Off-White

17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Usage And Synthesis

Uses

(16b)-17,21-Dihydroxy-16b-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.

17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione(13504-15-9)Related Product Information

• 11-Oxo-betaMethasone Dipropionate
• 9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
• Betamethasone Impurity 32
• Betamethasone EP Impurity F
• 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
• (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
• Betamethasone Acetate EP Impurity C
• Betamethasone Impurity 31
• Betamethasone
• Betamethasone 17-valerate
• Betamethasone EP Impurity H
• Betamethasone Tripropionate
• Betamethasone Impurity 8
• doxibetasol
• Betamethasone Impurity 7
• Beclomethasone dipropionate
• 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate
• 21-Dehydro BetaMethasone