Pyrithione Chemical Properties

Melting point:

68°C

Boiling point:

253.8±23.0 °C(Predicted)

Density 

1.255 (estimate)

refractive index 

1.5480 (estimate)

storage temp. 

2-8°C

solubility 

DMSO: 125 mg/mL (983.01 mM)

pka

4.70±0.20(Predicted)

form 

solid

Pyrithione Usage And Synthesis

Description

The sodium salt of N-hydroxy-2-pyridinethiones has a germicidal activity againts yeasts and fungi. Sodium omadine is a 40% aqueous solution of sodium pyrithione.

Uses

It is used in the metallurgical industry as a component of water-based metalwork fluids, of aceto-polyvinyl lattices, water-based printer's ink, lubrieant for synthetie fibers and anti-dandruff shampoos. A case was reported in a metallurgie worker.

Definition

ChEBI: A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn2+ ionophore; the zinc salt is used as an antifungal and antibacterial agent.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 4362, 1950 DOI: 10.1021/ja01166a008

Pyrithione(1121-30-8)Related Product Information

• tris(1-hydroxy-1H-pyridine-2-thionato-O,S)aluminium
• Copper Pyrithione
• 1-HYDROXY-2(1H)-PYRIDINETHIONE ZINC SALT
• Pyrithione