GABOXADOL HYDROCHLORIDE Chemical Properties

Melting point:

236 °C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

ethanol: soluble0.91mg/mL

form 

solid

color 

white

Merck 

14,4321

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

NY3396800

HS Code 

2934.99.9001

GABOXADOL HYDROCHLORIDE Usage And Synthesis

Uses

GABAergic Agonist

Uses

As a molecular probe to study GABA receptors.

Uses

Gaboxadol hydrochloride has been used in cell migration and invasion assay to assess liver cancer cell migration.

Uses

Gaboxadol is a sleep aid drug used for the treatment of chronic pain and insomnia. Gaboxadol is also known to exhibit antidepressant like properties through its agonistic activities towards GABA sites .

General Description

Gaboxadol, also referred to as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP), is a GABA site agonist. It has great affinity to the δ subunit of extrasynaptic high-affinity GABAA receptors. Gaboxadol was first developed for the treatment of schizophrenia, epilepsy, primary insomnia and Huntington′s disease. It can easily cross the blood-brain barrier and is rapidly absorbed by the body.

Biochem/physiol Actions

GABAA receptor agonist.

storage

Store at RT

GABOXADOL HYDROCHLORIDE(85118-33-8)Related Product Information

• TRIMETHYLENE OXIDE
• Aniline hydrochloride
• Trimethylamine hydrochloride
• Methylamine hydrochloride
• Betaine hydrochloride
• Dimethylamine hydrochloride
• THIP HYDROCHLORIDE