D-fructose 1,6-bis(dihydrogen phosphate) Chemical Properties

Melting point:

72--74°C

Boiling point:

819.8±75.0 °C(Predicted)

Density 

2.007±0.06 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Methanol (Slightly), Water (Slightly)

pka

1?+-.0.10(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

InChI

InChI=1S/C6H14O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3-,5-,6-/m1/s1

InChIKey

XPYBSIWDXQFNMH-UYFOZJQFSA-N

SMILES

C(OP(O)(O)=O)C([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=O

EPA Substance Registry System

D-Fructose, 1,6-bis(dihydrogen phosphate) (488-69-7)

Safety Information

RIDADR 

1759

TSCA 

TSCA listed

HazardClass 

8

PackingGroup 

III

D-fructose 1,6-bis(dihydrogen phosphate) Usage And Synthesis

Description

D-fructose 1,6-bis(dihydrogen phosphate) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma.

Chemical Properties

D-fructose 1,6-bis(dihydrogen phosphate) is a white or off-white crystalline powder that is soluble in water and virtually insoluble in ethanol, acetone and ether. In life activities, it participates in the synthesis and catabolism of ATP (adenosine triphosphate) as a carrier of high-energy phosphate bonds.

Uses

Cardioprotectant for ischemic disorders.

Definition

ChEBI: D-fructofuranose 1,6-bisphosphate is the furanose form of D-fructose 1,6-bisphosphate. It is functionally related to a D-fructofuranose. It is a conjugate acid of a D-fructofuranose 1,6-bisphosphate(4-).

Application

D-fructose 1,6-bis(dihydrogen phosphate) is an important metabolic intermediate and an energy carrier. It is primarily used in pharmaceuticals to provide a source of energy to cells and improve the metabolic rate of patients and also used in the food industry as a food additive due to its ability to enhance the aroma and taste of food products.

Mechanism of action

D-fructose 1,6-bis(dihydrogen phosphate) acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

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