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Phthaloyl amlodipine

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Phthaloyl amlodipine Basic information

Product Name:
Phthaloyl amlodipine
Synonyms:
  • 3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate
  • 1-Amino-6-fluoro-1,4-dihydro-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl)piperazin-1-yl)-4-oxo-[1,3]thiazeto[3,2-A]quinoline-3-carboxylic acid
  • 3-Ethyl-5-methyl-4-(2-chlorophenyl)-2-(2-phthalimidoethoxyl)methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • 4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-(phthalimidoethoxy)methyl-1,4-dihydropyridine
  • Phthalimidoamlodipine
  • 3,5-Pyridinedicarboxylicacid,4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]Methyl]-1,4-dihydro-6-Methyl-,3-ethyl 5-Methyl ester
  • 4-(2-Chlorophenyl)-3-Ethoxy carbonyl-5-Methoxy carbonil-6-Methyl-2-(phthaliMidoethoxy)Methyl-1,4-dihydropyridine
  • 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]Methyl]-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
CAS:
88150-62-3
MF:
C28H27ClN2O7
MW:
538.98
EINECS:
413-410-3
Product Categories:
  • API intermediates
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
88150-62-3.mol
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Phthaloyl amlodipine Chemical Properties

Melting point:
140-145°C
Boiling point:
654.1±55.0 °C(Predicted)
Density 
1.321±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
pka
2.06±0.70(Predicted)
color 
Pale Yellow to Light Yellow
PH
6.78 at 20.4℃ and 10g/L
InChIKey
AHHPZGUFLGCZCF-UHFFFAOYSA-N
SMILES
C1(COCCN2C(=O)C3=C(C2=O)C=CC=C3)NC(C)=C(C(OC)=O)C(C2=CC=CC=C2Cl)C=1C(OCC)=O
LogP
4.9 at 30℃ and pH6.79
CAS DataBase Reference
88150-62-3(CAS DataBase Reference)
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Safety Information

Risk Statements 
53
Safety Statements 
61
HS Code 
2933399090
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Phthaloyl amlodipine Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

Amilodopine intermediate

Uses

Amlodipine intermediate. Amlodipine Related Compound A

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