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TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE

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TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Basic information

Product Name:
TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE
Synonyms:
  • tert-Butyl 6-Chloro-(R)-hydroxy-3-oxohexanoate
  • Rosuvastatin Impurity 112
  • Hexanoic acid, 6-chloro-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (5R)-
  • (R)-tert-butyl 6-chloro-5-hydroxy-3-oxohexanoate
  • (R)-tert-butyl 6-chloro-5-hydroxy-3-oxohexanoate? (Rosuvastatin Impurity)
CAS:
404958-08-3
MF:
C10H17ClO4
MW:
236.69
Mol File:
404958-08-3.mol
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TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Chemical Properties

Boiling point:
331.1±32.0 °C(Predicted)
Density 
1.162±0.06 g/cm3(Predicted)
pka
10.33±0.46(Predicted)
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TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Usage And Synthesis

Uses

tert-Butyl 6-Chloro(R)-hydroxy-3-oxohexanoate is a chiral reagent used in the synthesis of callystatin A, a polyketide natural product that functions as an antibiotic. Also an impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.

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