Basic information Safety Supplier Related

Trichostatin C

Basic information Safety Supplier Related

Trichostatin C Basic information

Product Name:
Trichostatin C
Synonyms:
  • 7-[4-(Dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-2,4-heptadienamide
  • 145-A
  • 7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
  • (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
  • (2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
  • 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
CAS:
68676-88-0
MF:
C23H32N2O8
MW:
464.51
Mol File:
68676-88-0.mol
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Trichostatin C Chemical Properties

Melting point:
171-173°
alpha 
D24 +50.5 ±0.9° (c = 0.987 in methanol)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
pka
12.85±0.70(Predicted)
form 
White to off-white powder.
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Trichostatin C Usage And Synthesis

Uses

Trichostatin C is the first example of a glucopyranosyl hydroxamate from nature. The conjugation may act to protect the less stable N-OH group of Trichostatin A. Trichostatin C displays antifungal, antiprotozoan and antitumour activity, albeit less potent than trichostatin A

Uses

Trichostatin C is an inducer of erythroid differentiation and histone H4 acetylation level.

Definition

ChEBI: Trichostatin C is a trichostatin and an O-amino sugar. It is functionally related to a trichostatin A.

Trichostatin CSupplier

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Trichostatin C(68676-88-0)Related Product Information