Cinolazepam Chemical Properties

Melting point:

190-193°

Boiling point:

643.5±55.0 °C(Predicted)

Density 

1.39±0.1 g/cm3(Predicted)

form 

A neat solid

pka

11.53±0.40(Predicted)

Cinolazepam Usage And Synthesis

Description

Cinolazepam is a benzodiazepine hypnotic introduced first in Austria for the treatment of sleep disturbance due to somatic or environmental factors. It has a half-life of 9 hr and effectively restores disturbed sleep to normal but does not significantly affect normal sleep patterns. This compound is well tolerated and has been reported to have no hang-over side effect after sleep.

Originator

Gerot (Austria)

Uses

Cinolazepam is used as one of the substances for network-assisted prediction of potential drugs for addiction.

Definition

ChEBI: A 1,4-benzodiazepinone compound having a 2-cyanoethyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-fluorophenyl group at the 5-position and a chloro substituent at the 7-position, it has general properties similar to those of diazepam and has been used for the short-term management of sleep disorders.

brand name

Gerodorm

Cinolazepam(75696-02-5)Related Product Information

• N-Cyanoethyl-hydroxyethyl aniline
• 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
• Fludiazepam
• 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
• OXAZEPAM
• 3-HYDROXY-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE
• TEMAZEPAM
• N-(2-CYANOETHYL)-N-METHYLACETAMIDE
• N-desalkylflurazepam
• Cinolazepam