4-Methoxypiperidine Chemical Properties

Boiling point:

44°C/6.8mm

Density 

0.93

storage temp. 

2-8°C(protect from light)

form 

Liquid

pka

9.83±0.10(Predicted)

color 

Clear

InChI

InChI=1S/C6H13NO/c1-8-6-2-4-7-5-3-6/h6-7H,2-5H2,1H3

InChIKey

ZEYSHALLPAKUHG-UHFFFAOYSA-N

SMILES

N1CCC(OC)CC1

CAS DataBase Reference

4045-24-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

22-20/21/22

Safety Statements 

23-24/25

RIDADR 

3267

HS Code 

29339900

4-Methoxypiperidine Usage And Synthesis

Chemical Properties

Clear colorless liquid

Synthesis

The general procedure for the synthesis of 4-methoxypiperidine from the compound (CAS: 553672-12-1) was as follows: the compound (620 mg) obtained in step (1) was dissolved in methanol (20 mL) and 10% palladium-carbon catalyst (80 mg) was added. The reaction mixture was stirred for 3 hours at room temperature and under hydrogen atmosphere. Upon completion of the reaction, the reaction mixture was filtered through a membrane filter and the filtrate was concentrated under vacuum to afford 4-methoxypiperidine (290 mg, yield: 100%) as a light yellow oil. Mass spectrometry analysis (APCI) showed m/z: 116 [M + H]+.

References

[1] Patent: WO2007/46550, 2007, A1. Location in patent: Page/Page column 116-117

4-Methoxypiperidine(4045-24-3)Related Product Information

• Methoxydiethylborane
• POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE
• m-Anisyl alcohol
• Methoxyacetic acid
• p-Anisidine
• (Trifluoromethoxy)benzene
• p-Anisaldehyde
• Anisole
• 4-Methylpiperidine
• Homatropine Hydrobromide
• N-BENZYL-4-CHLORO-PIPERIDINE
• 1,4-Dioxa-8-azaspiro[4.5]decane
• lifibrate
• 4-Chloro-1-methylpiperidine hydrochloride
• 10,11-Dimethoxystrychnine
• Diphenylpyraline Hydrochloride
• STRYCHNINE
• BRUCINE SULFATE