D-OFLOXACIN Chemical Properties

Melting point:

185 °C

Boiling point:

571.5±50.0 °C(Predicted)

Density 

1.48±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

pka

5.19±0.40(Predicted)

color 

Off-white to light yellow

InChI

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m1/s1

InChIKey

GSDSWSVVBLHKDQ-SNVBAGLBSA-N

SMILES

O1C2=C(N3CCN(C)CC3)C(F)=CC3C(=O)C(C(O)=O)=CN(C2=3)[C@H](C)C1

Safety Information

HS Code 

2934990002

D-OFLOXACIN Usage And Synthesis

Uses

Fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).

Definition

ChEBI: Dextrofloxacin is the (R)-enantiomer of ofloxacin. It has a role as an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a topoisomerase IV inhibitor and a DNA synthesis inhibitor. It is a 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, a quinolone antibiotic and a fluoroquinolone antibiotic. It is an enantiomer of a levofloxacin.

D-OFLOXACIN(100986-86-5)Related Product Information

• Decarboxyl Ofloxacin
• 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
• Levofloxacin Related CoMpound E
• METHYLHYDROSILOXANE, DIMETHYLSILOXANE COPOLYMER, TRIMETHYLSILOXANE TERMINATED
• 3-Aminobenzotrifluoride
• Levofloxacin N-Oxide
• OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID)
• 2-Desisopropyl-2-phenyl Repaglinide
• Levofloxacin N-oxide
• ofloxacin O-glucuronide
• OFLOXACIN N-OXIDE (MIXTURE OF DIASTEREOMERS)
• Ofloxacin hydrochloride
• Desmethyl Levofloxacin
• Levofloxacin carboxylic acid
• Levofloxacin Related Compound C (25 mg) ((S)-ethyl 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate)
• N,N'-Desethylene Levofloxacin Hydrochloride
• 9-Piperazino Levofloxacin
• Descarboxyl Levofloxacin