Basic information Safety Supplier Related

D-OFLOXACIN

Basic information Safety Supplier Related

D-OFLOXACIN Basic information

Product Name:
D-OFLOXACIN
Synonyms:
  • D-OFLOXACIN
  • 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3R)- (9CI)
  • 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (R)-
  • DR 3354
  • [3R,(+)]-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
  • DS-4632
  • 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3R)-
  • Aids002308
CAS:
100986-86-5
MF:
C18H20FN3O4
MW:
361.37
Product Categories:
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
100986-86-5.mol
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D-OFLOXACIN Chemical Properties

Melting point:
185 °C
Boiling point:
571.5±50.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
pka
5.19±0.40(Predicted)
color 
Off-white to light yellow
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Safety Information

HS Code 
2934990002
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D-OFLOXACIN Usage And Synthesis

Uses

Fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).

Definition

ChEBI: Dextrofloxacin is the (R)-enantiomer of ofloxacin. It has a role as an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a topoisomerase IV inhibitor and a DNA synthesis inhibitor. It is a 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, a quinolone antibiotic and a fluoroquinolone antibiotic. It is an enantiomer of a levofloxacin.

D-OFLOXACINSupplier

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