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Nicotinic Acid Adenine Dinucleotide

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Nicotinic Acid Adenine Dinucleotide Basic information

Product Name:
Nicotinic Acid Adenine Dinucleotide
Synonyms:
  • 1-[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-3,4-dihydroxy-oxolan-2-yl]pyridine-5-carboxylate
  • Nicotinic acid adenine dinucleotide
  • SENPVEZBRZQVST-GDWWASDASA-N
  • ONAD
  • 1-[(2R,3R,4S,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]pyridin-1-ium-3-car
  • NAAD(O-NAD)
CAS:
6450-77-7
MF:
C21H26N6O15P2
MW:
664.41
Mol File:
6450-77-7.mol
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Nicotinic Acid Adenine Dinucleotide Chemical Properties

InChIKey
SENPVEZBRZQVST-KQGQPLBUNA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=O)[O-])=C3)O2)O)O[C@H]1N1C=NC2=C(N=CN=C12)N)O |&1:1,2,3,15,16,17,19,32,r|
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Nicotinic Acid Adenine Dinucleotide Usage And Synthesis

Uses

Nicotinic Acid Adenine Dinucleotide is an analog of β-Nicotinamide Adenine Dinucleotide (N407775, Hydrate); a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.

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