tert-Butyl 2-bromo-4-fluorobenzoate Chemical Properties

Boiling point:

305.7±27.0 °C(Predicted)

Density 

1.394±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Oil

color 

Clear Colourless

Safety Information

HS Code 

2916399090

tert-Butyl 2-bromo-4-fluorobenzoate Usage And Synthesis

Uses

tert-Butyl 4-Bromo-2-fluorobenzoate is an intermediate of enzalutamide (M199800). Enzalutamide is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.

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