ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > CAPTOPRIL DISULFIDE
CAPTOPRIL DISULFIDE
CAPTOPRIL DISULFIDE Basic information
- Product Name:
- CAPTOPRIL DISULFIDE
- Synonyms:
-
- CAPTOPRIL DISULFIDE
- CAPTOPRIL DISULFIDE USP
- CAPTOPRIL DISULFIDE USP(CRM STANDARD)
- CAPTOPRIL DISULFIDE WHO(CRM STANDARD)
- CAPTOPRIL DISULPHIDE BP STANDARD
- Captopril ImpurityⅠ:Captopril Disulfide{ 1,1'-[Dithiobis[(2S)-2-methyl-1-oxo-3,1-propanediyl]]bis-L-proline CAPTOPRDS}
- Imp. A (EP):1,1'-[Disulfanediylbis-[(2S)-2-methyl-1-oxopropane-3,1-diyl]]-bis[(2S)-pyrrolidine-2-carboxylic] Acid(Captopril Disulfide)
- Captopril Impurity A
- CAS:
- 64806-05-9
- MF:
- C18H28N2O6S2
- MW:
- 432.55
- Product Categories:
-
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 64806-05-9.mol
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CAPTOPRIL DISULFIDE Chemical Properties
- Melting point:
- 224-226°C
- Boiling point:
- 714.8±60.0 °C(Predicted)
- Density
- 1.383±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 3.29±0.20(Predicted)
- color
- White to Off-White
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CAPTOPRIL DISULFIDE Usage And Synthesis
Description
Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril . Captopril disulfide is the main degradation product of captopril and is formed by oxidation. It is a potential impurity in commercial preparations of captopril. Captopril disulfide inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.).
Chemical Properties
White Solid
Uses
Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent.
Definition
ChEBI: An organic disulfide in which the disulfide bond links two units of captopril. It is a secondary metabolite of captopril.
CAPTOPRIL DISULFIDESupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Sinopharm Chemical Reagent Co,Ltd.
- Tel
- 86-21-63210123
- sj_scrc@sinopharm.com
Spectrum Chemical Manufacturing Corp.
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- marketing_china@spectrumchemical.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
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CAPTOPRIL DISULFIDE(64806-05-9)Related Product Information
- Ion pair reagent
- Captopril
- 1-[(2R)-3-Hydroxy-2-Methyl-1-oxopropyl]-L-proline
- Canagliflozin Dimer
- alpha-Capecitabine
- 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
- CAPECITABINE related substance USP
- (2S)-1-[(2S)-2-Methyl-3-Methylsulfinylpropanoyl]pyrrolidine-2-carboxylic acid
- 5'-deoxy-5-fluore-N-[(pentoyloxy)carbonyl]cytidine 2',3'-diacetate
- pentyl(1-((2R,3R,4R,5R)-3,4-bis(((2S,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)oxy)-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate
- 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine
- 5'-Deoxy-5-fluorocytidine
- 1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline
- (2S)-1-[2-Methylpropanoyl]-pyrrolidine-2-carboxylic Acid
- Captopril tablets
- DIISOBUTYL DISULFIDE
- CAPTOPRIL DISULFIDE
- CAPTOPRIL IMP. A (EP): CAPTOPRIL DISULPHIDE MM