Ethyl 2-chloropropionate Chemical Properties

Boiling point:

146-149 °C (lit.)

Density 

1.072 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.417(lit.)

Flash point:

101 °F

storage temp. 

Flammables area

solubility 

alcohol: miscible

form 

clear liquid

color 

Colorless to Light yellow

Specific Gravity

1.085 (20/4℃)

Water Solubility 

immiscible

Merck 

14,3785

BRN 

773906

Dielectric constant

10.1

LogP

1.382 (est)

CAS DataBase Reference

535-13-7(CAS DataBase Reference)

NIST Chemistry Reference

Ethyl 2-chloropropionate(535-13-7)

EPA Substance Registry System

Ethyl-2-chloropropionate (535-13-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-36-37/39-16

RIDADR 

UN 2935 3/PG 3

WGK Germany 

3

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29159000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Ethyl 2-chloropropionate Usage And Synthesis

Description

Ethyl-2-chloropropionate is a liquid with apleasant odor. Molecular weight = 136.8; Boilingpoint = 147℃; Flash point = 41.8℃

Chemical Properties

clear colorless liquid

Chemical Properties

Ethyl-2-chloropropionate is a liquid with a pleasant odor

Uses

Ethyl 2-chloropropionate was used as initiator during the synthesis of poly(2-(diethylamino)ethyl methacrylate) and poly(N-isopropylacrylamide) via atom transfer radical polymerization. It was also used in the synthesis of end-functionalized poly(N-isopropylacrylamide) with pyrenyl group.

General Description

A clear colorless liquid with a pungent odor. Flash point of 100°F. Denser than water and insoluble in water. Vapors are heavier than air.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Ethyl 2-chloropropionate is a halogenated ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Potential Exposure

This material is used in organic synthesis.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24- 48 h afterbreathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a corticosteroid spray.

storage

Color Code—Red: Flammability Hazard: Store in aflammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with this chemical you should be trained onits proper handling and storage. Store in tightly closed containers in a cool, well-ventilated area away from acids, bases,oxidizing and reducing agents. Sources of ignition, such assmoking and open flames, are prohibited where ethyl-2-chloropropionate is used, handled, or stored in a manner thatcould create a potential fire or explosion hazard

Shipping

UN2935 Ethyl 2-chloropropionate, Hazard Class: 3; Labels: 3-Flammable liquid.

Incompatibilities

Flammable liquid; forms explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, and reducing agents. Esters are generally incompatible with nitrates. Moisture may cause hydrolysis or other forms of decomposition. Esters react with acids releasing heat in addition to alcohols and acids. Contact with caustic solutions generate heat. Contact with esters with alkali metals and hydrides releases flammable hydrogen.

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