Basic information Safety Supplier Related

bakkenolide A

Basic information Safety Supplier Related

bakkenolide A Basic information

Product Name:
bakkenolide A
Synonyms:
  • bakkenolide A
  • (2R,3aR,7S,7aR)-7,7a-dimethyl-4'-methylidenespiro[3,3a,4,5,6,7-hexahydro-1H-indene-2,3'-oxolane]-2'-one
  • (3R)-1',3',3'a,4,4',5,5',6',7',7'aβ-Decahydro-3'aβ,4'β-dimethyl-4-methylenespiro[furan-3(2H),2'-[2H]inden]-2-one
  • (3R,3'aR,7'aβ)-3'aβ,4'β-Dimethyl-4-methylenespiro[oxolane-3,2'-hydrindane]-2-one
  • Bakkenolid a
  • Fukinanolid
  • Nsc 292655
  • Spiro(furan-3(2H),2'-(2H)inden)-2-one, decahydro-3'A,4'-dimethyl-4-methylene-, (2'R-(2'alpha,3'aalpha,4'alpha,7'aalpha))- (9ci)
CAS:
19906-72-0
MF:
C15H22O2
MW:
234.33
Mol File:
19906-72-0.mol
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bakkenolide A Chemical Properties

Melting point:
80-81℃
Density 
1.06
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
color 
White to off-white
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bakkenolide A Usage And Synthesis

Uses

Bakkenolide A is a natural product extracted from Petasites tricholobus. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways[1].

Definition

ChEBI: Bakkenolide A is a sesquiterpenoid.

target

HDAC | IkB | IL Receptor | Caspase | TNF-α | PI3K | Akt | GSK-3 | IKK

References

[1] Zhang L, et al. Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways. Biomed Pharmacother. 2016 Oct;83:958-966. DOI:10.1016/j.biopha.2016.07.049

bakkenolide ASupplier

Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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Cheng Du Pufeide Biotechnology Co., Ltd.
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028-82610909 13388174823
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Shanghai BeiZhuo Biotech Co., Ltd.
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021-61119791,13386096464
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Shanghai Aspire Biological Technology Co., Ltd.
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021-61317773
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Shanghai Yongye Biotechnology Co., Ltd.
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86-021-61559134 15921386130
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3423497944@qq.com
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bakkenolide A(19906-72-0)Related Product Information