atrasentan
atrasentan Basic information
- Product Name:
- atrasentan
- Synonyms:
-
- atrasentan
- (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
- (+)-A 127722
- A-147627
- (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
- (2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
- A127722, CID 5310990
- Atrasentan (ABT-627)
- CAS:
- 173937-91-2
- MF:
- C29H38N2O6
- MW:
- 510.62
- Product Categories:
-
- API
- Mol File:
- 173937-91-2.mol
More
Less
atrasentan Chemical Properties
- Melting point:
- 122-124°
- Boiling point:
- 659.4±55.0 °C(Predicted)
- Density
- 1.188±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.49±0.60(Predicted)
- color
- Off-White
More
Less
atrasentan Usage And Synthesis
Uses
Palliative treatment of bone pain due to metastatic prostate cancer and disease progression (endothelin (ETA) receptor antagonist).
Uses
Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
Definition
ChEBI: Atrasentan is a member of pyrrolidines.
atrasentanSupplier
Wuhan Ruilida Biomedical Technology Co., Ltd. Gold
- Tel
- 18201884268
- magean83@163.com
Bayee Biotech (Anqing) Co., Ltd. Gold
- Tel
- 0556-5032306 18917961636
- wtx@bayeebio.com
Shanghai Hope Chem Co., Ltd.， Gold
- Tel
- +21-18501659228 18501659228
- info@hope-chem.com
Suzhou Haiben Pharmaceutical Co., Ltd Gold
- Tel
- 14760821013 13564957716
- 1816280386@qq.com
Nantong Hanfang Biotechnology Co. , Ltd. Gold
- Tel
- 18616537568
- hanfangpharma@126.com