Diethyl ethylmalonate Chemical Properties

Melting point:

0°C

Boiling point:

75-77 °C/5 mmHg (lit.)

Density 

1.004 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.416(lit.)

Flash point:

191 °F

storage temp. 

Store below +30°C.

solubility 

2.87g/l

form 

Liquid

pka

13.17±0.46(Predicted)

color 

Clear colorless

PH

4.46 at 24.3℃ and 10g/L

Water Solubility 

immiscible

BRN 

607635

LogP

2.4 at 30℃ and pH7.93

CAS DataBase Reference

133-13-1(CAS DataBase Reference)

NIST Chemistry Reference

Propanedioic acid, ethyl-, diethyl ester(133-13-1)

EPA Substance Registry System

Propanedioic acid, ethyl-, diethyl ester (133-13-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

24/25-36-26

WGK Germany 

2

TSCA 

Yes

HS Code 

29171990

Toxicity

LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rat > 2000 mg/kg

MSDS

• Language:English Provider:Diethyl ethylmalonate
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Diethyl ethylmalonate Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Diethyl Ethylmalonate is used in the synthesis of HIV-1 reverse transcriptase inhibitors. Also used in the preparation of Peloruside A, a novel antimitotic agent used as a potential anti-cancer agent.

Diethyl ethylmalonate(133-13-1)Related Product Information

• Ethylene glycol diethyl ether
• Diethyl isopropylmalonate
• Diethyl bis(hydroxymethyl)malonate
• 2-AMINODIETHYLMALONATE
• Diethyl oxalate
• Diethyl malonate
• Diethyl benzylmalonate
• DIETHYL ETHYLPHOSPHONATE
• Diethyl butylmalonate
• Diethyl dibutylmalonate
• DIETHYL DIMETHYLMALONATE
• Mefenpyr-diethyl
• Diethyl ketomalonate
• Ethyl malonyl chloride
• Diethyl phenylmalonate
• Diethyl dipropylmalonate
• Diethyl methylmalonate
• ETHYLMALONIC ACID