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(+)-CATECHIN HYDRATE

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(+)-CATECHIN HYDRATE Basic information

Product Name:
(+)-CATECHIN HYDRATE
Synonyms:
  • FK-027-13C,15N2
  • FR- 17027-13C,15N2
  • (+)-Catechin hydrate >=96.0% (suM of enantioMers, HPLC)
  • (2R,3S)-2-(3,4-Dihydroxyphenyl)-chroman-3,5,7-triol hydrate
  • 2-keto-4-methyl-6-phenyl-3,6-dihydro-1H-pyrimidine-5-carboxylic acid methyl ester
  • 4-methyl-2-oxo-6-phenyl-3,6-dihydro-1H-pyrimidine-5-carboxylic acid methyl ester
  • BAS 00381104
  • EU-0067758
CAS:
225937-10-0
MF:
C15H16O7
MW:
308.29
EINECS:
684-232-3
Product Categories:
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
225937-10-0.mol
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(+)-CATECHIN HYDRATE Chemical Properties

Melting point:
175-177 °C (anhydrous)(lit.)
alpha 
26 º (C=1 IN H2O)
storage temp. 
2-8°C
solubility 
ethanol: soluble50mg/mL
form 
powder
color 
yellow to yellow with tan cast
optical activity
[α]/D +26±2°, c = 1 in H2O
Merck 
13,1912
BRN 
3595244
CAS DataBase Reference
225937-10-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
8-10-23
HS Code 
29329990

MSDS

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(+)-CATECHIN HYDRATE Usage And Synthesis

Uses

(+)-Catechin hydrate can be used:

  • As an inhibitor of steel corrosion in hydrochloric acid solution.
  • As a model compound in the study of antimicrobial activities of flavonoids on Escherichia coli.
  • As a starting material for the synthesis of catechin glucosides of biological importance.

Uses

(+)-Catechin hydrate has been used:

  • as a polyphenol standard in the determination of total polyphenols in the by-products of red wine
  • as an additive to study its effects on in vitro methane production and substrate degradation in a triple-fed batch approach
  • as a substrate to determine the activity of pure L. plantarum CECT 748T 14 recombinant tannase on catechin

Definition

ChEBI: (+)-catechin monohydrate is the monohydrate of (+)-catechin. It has a role as a geroprotector. It contains a (+)-catechin.

General Description

Catechin hydrate is a polyphenolic flavonoid that exhibits antioxidant properties. It is commonly found in green tea, grape seeds, and bark of few trees like acacia and mahogany.

Biochem/physiol Actions

An antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. For example, at physiological pH catechin suppressed DNA strand breaks by hydroxyl radicals. It has also been shown to prevent human plasma oxidation. It delayed the consumption of endogenous lipid-soluble antioxidants and inhibited lipid oxidation. Catechin may also function as an inhibitor of fatty acid synthase.

target

COX-1

(+)-CATECHIN HYDRATESupplier

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