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dipsacoside B

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dipsacoside B Basic information

Product Name:
dipsacoside B
Synonyms:
  • dipsacoside B
  • BRS013840
  • (3beta,4alpha)-3-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid, 6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl ester
  • Glycoside L-G3
  • Dipsacoside B(Glycoside L-G3)
  • Tauroside G3
  • Dipsacoside B, 98%, from Lonicera confusa (Sweet) DC.
  • Dipsacoside B 33289-85-9
CAS:
33289-85-9
MF:
C53H86O22
MW:
1075.24
EINECS:
618-347-7
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
33289-85-9.mol
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dipsacoside B Chemical Properties

Density 
1.46
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMF: 12 mg/mL; DMSO: 16 mg/mL; Ethanol: 5 mg/mL; PBS (pH 7.2): 5 mg/mL
form 
A solid
pka
12.50±0.70(Predicted)
color 
White to off-white
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Safety Information

Safety Statements 
24/25
HS Code 
29389090
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dipsacoside B Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol and ethanol, derived from honeysuckle.

Uses

Dipsacoside B is a cytotoxic biactive saponin naturally occurring from the buds of the Lonicera macranthides plant

in vivo

A liquid chromatography-electrospray ionization-mass spectrometry method has been developed and validated for identification and quantification of four major bioactive saponins in rat plasma after oral administration of extraction of saponins from Flos Lonicerae, i.e., Macranthoidin B, Macranthoidin A, Dipsacoside B, and Macranthoside B. The retention time of Macranthoidin B, Macranthoidin A, Dipsacoside B, Macranthoside B and IS are 10.65, 12.11, 13.81, 23.31 and 5.47 min, respectively[1]. Taking Macranthoidins A, B, Dipsacoside B (saponins), sweroside (iridoids), and luteolin-7-O-d-glucoside (flavonoids) as markers, a method of ultra high performance liquid chromatography with triple quadrupole mass spectrometry is employed to determine their amounts in Lonicerae Flos, Lonicerae Japonicae Flos, and Lonicerae Japonicae Flos preparations[2].

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