5-BROMO-2-IODO-M-XYLENE Chemical Properties

Melting point:

42 °C

Boiling point:

282℃

Density 

1.940

Flash point:

125℃

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

form 

fused solid

color 

Faint peach

CAS DataBase Reference

206559-43-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HazardClass 

IRRITANT

HS Code 

2903998090

5-BROMO-2-IODO-M-XYLENE Usage And Synthesis

Synthesis

The diazotization reaction was carried out using sodium nitrite and hydrochloric acid in acetonitrile solvent at 0 °C using 4-bromo-2,6-dimethylaniline as starting material. Subsequently, the diazonium group was converted to iodine by addition of potassium iodide to afford the target product 5-bromo-2-iodo-1,3-xylene in 96% yield. The synthesis was described with reference to known literature (NonPatentDocument 2).

References

[1] Journal of Medicinal Chemistry, 2018, vol. 61, # 16, p. 7202 - 7217
[2] Patent: JP5959171, 2016, B2. Location in patent: Paragraph 0258-0260
[3] Bulletin of the Chemical Society of Japan, 2001, vol. 74, # 11, p. 2207 - 2218
[4] Patent: WO2009/74314, 2009, A1. Location in patent: Page/Page column 168-169

5-BROMO-2-IODO-M-XYLENE(206559-43-5)Related Product Information

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