ChemicalBook > Product Catalog > Biochemical Engineering > nucleic acid drugs > 3-methylpseudouridine
3-methylpseudouridine
3-methylpseudouridine Basic information
- Product Name:
- 3-methylpseudouridine
- Synonyms:
-
- 3-methylpseudouridine
- NSC 363818
- 3-Methyl-5-beta-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
- 3-Methylpsedouridine
- N3-Methylpseudouridine
- 3-Methylpseudouridine, RNA modified nucleoside, m3?, Pseudouridine impurity
- 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
- 2,4(1H,3H)-Pyrimidinedione, 3-methyl-5-β-D-ribofuranosyl-
- CAS:
- 81691-06-7
- MF:
- C10H14N2O6
- MW:
- 258.22796
- Product Categories:
-
- Pharmaceutical
- Mol File:
- 81691-06-7.mol
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3-methylpseudouridine Chemical Properties
- Density
- 1.576±0.06 g/cm3(Predicted)
- pka
- 9.88±0.10(Predicted)
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3-methylpseudouridine Usage And Synthesis
Uses
3-Methylpseudouridine is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival.
Uses
3-Methylpseudouridine (CAS# 81691-06-7) is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival.
Definition
ChEBI: 3-Methylpseudouridine is a carbohydrate derivative and a nucleobase-containing molecular entity.
Synthesis
ψ-Uridine was trimethylsilylated and the crude product was treated with acetyl chloride, to give the 1-acetyl derivative (3). Crude 3 was methylated with dimethoxymethyldimethylamine and then saponified, to give crystalline 3-methyl-ψ-uridine in 82% overall yield.
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