Chebulinic acid Chemical Properties

Boiling point:

1460.0±65.0 °C(Predicted)

Density 

2.04

storage temp. 

-20°C

solubility 

Soluble in acetone, methanol and hot water; insoluble in chloroform and n-hexane

form 

powder

pka

4.14±0.10(Predicted)

color 

Beige

InChIKey

YGVHOSGNOYKRIH-KOPSEHRPNA-N

Safety Information

WGK Germany 

3

Chebulinic acid Usage And Synthesis

Uses

Chebulinic Acid has been shown to prevent epithelial mesenchymal transition in retinal pigment epithelial cells through inhibition of SMAD-3 phosphorylation. This prevents retinal detachment in the process of proliferative vitreoretinopathy.

Definition

ChEBI: Chebulinic acid is a tannin.

Origin

Chebulinic acid, an ellagitannin found commonly in Terminalia chebula, has been used extensively to treat diverse eras of ailments traditionally. It was also present in Phyllanthus emblica, Dimocarpus longan, Terminalia catappa, Terminalia parviflora, Terminalia macroptera, Lumnttzera racemosa, and Dendrophthoe falcate and has been used extensively in the traditional Indian system of medicine. It was first isolated by Fridolin in the year 1884[1].

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