Basic information Safety Supplier Related

N-trifluoroacetyladriamycin

Basic information Safety Supplier Related

N-trifluoroacetyladriamycin Basic information

Product Name:
N-trifluoroacetyladriamycin
Synonyms:
  • (8S,10S)-7,8,9,10-Tetrahydro-8-(hydroxyacetyl)-1-methoxy-10-[[3-(trifluoroacetylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-6,8,11-trihydroxy-5,12-naphthacenedione
  • AD-41
  • N-Trifluoroacetyldoxorubicin
  • (1S,3S)- α-2,3,6-trideoxy-3-(2,2,2-trifluoroacetaMido)-3-glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-Methoxy-6,11-dioxo-1-naphthacenyl L-lyxo-Hexopyranoside
  • (8S-cis)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-Methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)aMino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione
  • NSC 283464
  • 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
  • 2,2,2-Trifluoro-N-((2S,3S,4S,6R)-3-hydroxy-2-methyl-6-(((1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)tetrahydro-2H-pyran-4-yl)acetamide (Doxorubicin Impurity)
CAS:
26295-56-7
MF:
C29H28F3NO12
MW:
639.53
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
26295-56-7.mol
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N-trifluoroacetyladriamycin Chemical Properties

Melting point:
>150°C (dec.)
Boiling point:
855.4±65.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
solubility 
DMSO, Methanol
pka
7.35±0.60(Predicted)
form 
Solid
color 
Red
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Safety Information

Toxicity
dnd-hmn-lym 1 mg/L CNREA8 39,448,1979
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N-trifluoroacetyladriamycin Usage And Synthesis

Chemical Properties

Red Solid

Uses

Doxorubicin (D558000) metabolite. Cytotoxic interaction with DNA.

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx andFí.

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