1-(4-Isobutylphenyl)ethanol
1-(4-Isobutylphenyl)ethanol Basic information
- Product Name:
- 1-(4-Isobutylphenyl)ethanol
- Synonyms:
-
- α-Methyl-4-(2-Methylpropyl)benzeneMethanol
- Ibuprofen IMpurity-Q(EP/BP)
- 1-[4-(2-methylpropyl)phenyl]ethanol
- Ibuprofen Impurity 32
- Ibuprofen Impurity 3 (1-(4-Isobutylphenyl)Ethanol)
- 1-[4-(2-METHYLPROPYL)PHENYL]ETHAN-1-OL
- (1-HYDROXYETHYL)-4-ISOBUTYLBENZENE
- (1-HYDROXYETHYL)-4-(2-METHYLPROPYL)BENZENE
- CAS:
- 40150-92-3
- MF:
- C12H18O
- MW:
- 178.27
- EINECS:
- 641-487-5
- Product Categories:
-
- Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 40150-92-3.mol
1-(4-Isobutylphenyl)ethanol Chemical Properties
- Boiling point:
- 111 °C(Press: 1 Torr)
- Density
- 0.954±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 14.53±0.20(Predicted)
- color
- Colourless
- EPA Substance Registry System
- Benzenemethanol, .alpha.-methyl-4-(2-methylpropyl)- (40150-92-3)
1-(4-Isobutylphenyl)ethanol Usage And Synthesis
Uses
1-(4-Isobutylphenyl)ethanol is a photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.
Preparation
1-(4-Isobutylphenyl)ethanol synthesis: A solution of p-isobutylacetophenone (1.20mL), methanol (3.00mL), and sodium borohydride (0.2509g) was mixed in a separatory funnel and allowed to sit for 10min. After the standing time period, a 10 % HCl solution (10.0 mL) was added to remove any unreacted sodium borohydride, and the product was extracted using petroleum ether. 1-(4-Isobutylphenyl)ethanol product (1.002g, 87.2%) was collected and dried using anhydrous sodium sulfate.
1HNMR (300MHz, CDCl3): δ7.281 (2H, m, J = 4.0 Hz), δ7.174 (2H, m, J = 4.0 Hz), δ4.855 (1H, s, J =0.92Hz), δ2.714 (3H, q, J =2.2Hz), δ2.554 (2H, t, J = 2.8 Hz), δ1.795 (1H, q, J = 2.7 Hz), δ1.484 (1H, m, J =2.8Hz), δ0.976 (6H, q, J =6.1Hz). 13C NMR (300 MHz, CDCl3): 143.325, 140.684, 129.143, 125.357, 70.034, 45.196, 30.343, 25.076, 22.725, 22.465.
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1-(4-Isobutylphenyl)ethanol(40150-92-3)Related Product Information
- Ibuprofen
- Ibuprofen Ester Impurity
- 2-(4-Methylphenyl)propanoic acid
- 1,3-bis(4-isobutylphenyl)butan-1-one
- Ibuprofen Ethyl Ester
- 1-Oxo Ibuprofen
- Ibuprofen Isopropyl Ester
- 1-Hydroxyibuprofen
- 2-(4-isobutylphenyl)propionaldehyde
- Ibuprofen Impurity 4
- 4'-(2-Methylpropyl)acetophenone
- 4-(2-Methylpropyl)benzeneethanol
- 4-Benzyloxybenzaldehyde
- Ibuprofen EP Impurity I
- 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID
- Ibuprofen Impurity 2
- CARBOXYIBUPROFEN
- p-Isobutylstyrene