Licochalcone B Chemical Properties

Melting point:

196-197℃

Boiling point:

550.5±50.0 °C(Predicted)

Density 

1.369±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. 

Store at -20°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

powder

pka

7.80±0.15(Predicted)

color 

White

Licochalcone B Usage And Synthesis

Chemical Properties

Licochalcone B is a yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents,and it is derived from licorice rhizomes.

Uses

Licochalcone B has anti-tumor, anti-inflammatory, and antioxidant effects.It can be used for content determination, identification, pharmacological experiments, etc.

Definition

ChEBI: Licochalcone B is a member of chalcones.

Biological Activity

Licochalcone B is extracted from Glycyrrhizainflate root. LICOCHALCONEB inhibits the self-aggregation of amyloid β (Aβ420) (IC50=2.16 μM) and disintegrates pre-formed Aβ42 fibrils, reducing metal-induced Aβ42 aggregation by chelating metal ions.

Licochalcone B(58749-23-8)Related Product Information

• LIQUIRITIN(SH)
• Licoflaven B
• ISOLIQUIRITIN
• Glycyrrhizic acid
• neoliquiritin
• Isoliquiritigenin
• Neoisoliquiritin
• 3β,22β-Dihydroxy-11-oxoolean-12-en-30-oic acid γ-lactone
• Glabrone
• Licochalcone E
• Licoflavone C
• GLABROL
• 2-Propen-1-one, 3-(3,4-dihydroxy-2-Methoxyphenyl)-1-[4-hydroxy-3-(3-Methyl-2-butenyl)p henyl]-, (E)-
• Dipotassium glycyrrhizinate
• isoliquiritin apioside
• 5,7-Dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-4H-1-benzopyran-4-one
• LICOCHALCONE-A
• LICOCHALCONEC