4-Chlorobenzyl chloride Chemical Properties

Melting point:

27-29 °C (lit.)

Boiling point:

216-222 °C (lit.)

Density 

1.26

Flash point:

208 °F

refractive index 

1.5575

storage temp. 

Store at RT.

solubility 

insoluble

form 

Crystalline Low Melting Solid

Specific Gravity

1.26

color 

Colorless to white

Water Solubility 

insoluble

Sensitive 

Lachrymatory

BRN 

471558

Stability:

Moisture Sensitive

CAS DataBase Reference

104-83-6(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-chloro-4-(chloromethyl)-(104-83-6)

EPA Substance Registry System

4-Chlorobenzyl chloride (104-83-6)

Safety Information

Hazard Codes 

C,N,Xn

Risk Statements 

34-51/53-20/21/22-52/53-43-22

Safety Statements 

26-36/37/39-45-29-61-36/37

RIDADR 

UN 3427 6.1/PG 3

WGK Germany 

2

RTECS 

XT0720000

F 

19-21

Hazard Note 

Corrosive/Lachrymatory

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29049090

Hazardous Substances Data

104-83-6(Hazardous Substances Data)

MSDS

• Language:English Provider:4-Chlorobenzyl chloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Chlorobenzyl chloride Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

Reagent used in derivatization of, for example, a calix[4]arene1 and a tryptamine.2

Uses

4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.

Uses

4-Chlorobenzyl chloride was the test compound for determining rat hepatocellular thiols by HPLC. As a reagent used in derivatization of, for example, a calix[4]arene and a tryptamine. It is widely used as an intermediate for manufacturing organic compounds like benzyl alcohol and benzyl cyanide. Also used in fuel as a gum inhibitor.

General Description

4-Chlorobenzyl chloride is generally used in the preparation of quaternary ammonium salts. It acts as an intermediate in the production of rice herbicide, pharmaceuticals and pesticides.

Hazard

Irritating to skin, eyes.

Purification Methods

Dry it over CaSO4, then fractionally distil it under reduced pressure. Crystallise it from heptane or dry diethyl ether at low temperature. [Beilstein 5 IV 816.] LACHRYMATORY.

4-Chlorobenzyl chloride(104-83-6)Related Product Information

• 4-Chlorobenzylamine
• Thionyl chloride
• 2-(Chloromethyl)benzonitrile
• 2-(4-Chlorobenzyl)pyridine
• Diethylstilbestrol
• Benzyltriethylammonium chloride
• Benzyltrimethylammonium chloride
• Calcium chloride
• Choline chloride
• Ammonium chloride
• Benzyl chloroformate
• 4-Chlorobenzyl alcohol
• Polyvinyl chloride
• Sodium chloride
• 4-Methylbenzyl chloride
• Benzyl chloride
• 4-Methoxybenzylchloride
• 2,6-Dichlorotoluene