1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE Chemical Properties

Melting point:

172-173℃

Boiling point:

760.2±70.0 °C(Predicted)

Density 

0.996

storage temp. 

-20°C

solubility 

Chloroform (Slightly, Heated, Sonicated)

form 

Solid

pka

1.17±0.50(Predicted)

color 

White to Off-White

BRN 

1730641

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

10-21

HS Code 

29232000

MSDS

• Language:English Provider:SigmaAldrich

1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE Usage And Synthesis

Chemical Properties

White powder

Uses

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine is used in the generation of micelles and liposomes.

Definition

ChEBI: (R)-1,2-distearoylphosphatidylethanolamine is an optically active form of 1,2-distearoylphosphatidylethanolamine having (R)-configuration. It has a role as a mouse metabolite. It is an enantiomer of a (S)-1,2-distearoylphosphatidylethanolamine. It is a tautomer of a (R)-1,2-distearoylphosphatidylethanolamine zwitterion.

General Description

Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in biological membranes. Phosphatidylethanolamine is found in nervous tissue.

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures. It modulates membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays an important role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.

Purification Methods

The R-form is recrystallised from CHCl3/MeOH, and the ±-form is recrystallised from EtOH. [Bevan & Malkin J Chem Soc 2667 1951, Baer Can J Biochem Physiol 81 1758 1959, Beilstein 4 IV 1420.]

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