PHYTOLACCOSIDEB CAS#: 60820-94-2

PHYTOLACCOSIDEB Basic information

Product Name:

PHYTOLACCOSIDEB

Synonyms:

PHYTOLACCOSIDEB
(4R,20S)-3β-(β-D-Xylopyranosyloxy)-2β,23-dihydroxyolean-12-ene-28,30-dioic acid 30-methyl ester
2β,23-Dihydroxy-3β-(β-D-xylopyranosyloxy)oleana-12-ene-28,30-dioic acid 30-methyl ester
3β-(β-D-Xylopyranosyloxy)-2β,23-dihydroxyoleana-12-ene-28,30-bisoic acid 30-methyl ester
(2beta,3beta,4alpha,20beta)-2,23-Dihydroxy-3-(beta-D-xylopyranosyloxy)olean-12-ene-28,29-dioic acid 29-methyl ester
Phytolaccasaponin G
Olean-12-ene-28,29-dioicacid, 2,23-dihydroxy-3-(b-D-xylopyranosyloxy)-, 29-methyl ester, (2b,3b,4a,20b)-
Olean-12-ene-28,29-dioic acid, 2,23-dihydroxy-3-(β-D-xylopyranosyloxy)-, 29-methyl ester, (2β,3β,4α,20β)-

CAS:

60820-94-2

MF:

C36H56O11

MW:

664.82

EINECS:

200-258-5

Product Categories:

Triterpenoids

Mol File:

60820-94-2.mol

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PHYTOLACCOSIDEB Chemical Properties

Boiling point:: 779.3±60.0 °C(Predicted)
Density: 1.33
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
pka: 4.39±0.70(Predicted)
color: White

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PHYTOLACCOSIDEB Usage And Synthesis

Uses

Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].

Definition

ChEBI: Phytolaccoside B is a triterpenoid.

target

Antifection

References

[1] Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163. DOI:10.1016/j.intimp.2019.01.003
[2] Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777. DOI:10.1016/j.fct.2023.113777
[3] Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725. DOI:10.1021/np070660i

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