Triamcinolone 21-acetate Chemical Properties

Melting point:

212-215 °C(Solv: acetone (67-64-1); ethyl ether (60-29-7))

Boiling point:

596.0±50.0 °C(Predicted)

Density 

1.38±0.1 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly, Sonicated, Heated)

form 

Solid

pka

11.52±0.70(Predicted)

color 

White to Off-White

Triamcinolone 21-acetate Usage And Synthesis

Description

Triamcinolone 21-acetate is a synthetic anti-inflammatory drug with a triamcinolone core. It has been used for the treatment of inflammatory conditions such as arthritis and allergic disorders. The mechanism of action is unknown, but it is thought to involve the inhibition of prostaglandin synthesis by inhibiting enzymes that are involved in prostaglandin biosynthesis. Triamcinolone 21-acetate is effective against rheumatoid arthritis and other inflammatory disorders. This drug also has anti-bacterial activity, which may be due to its ability to inhibit cell membrane function or interfere with protein synthesis.

Uses

Triamcinolone 21-Acetate is an impurity of Triamcinolone (T767160), a glucocorticoid used as an antiasthmatic.