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4-NITRO-3-(TRIFLUOROMETHYL)PHENOL

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4-NITRO-3-(TRIFLUOROMETHYL)PHENOL Basic information

Product Name:
4-NITRO-3-(TRIFLUOROMETHYL)PHENOL
Synonyms:
  • 3-TRIFLUOROMETHYL-4-NITROPHENOL
  • 4-NITRO-A,A,A-TRIFLUORO-M-CRESOL
  • 4-nitro-3-(trifluoromethyl)-pheno
  • 4-nitro-3-(trifluoromethyl)phenolsodiumsalt
  • 4-NITRO-3-(TRIFLUOROMETHYL)PHENOL
  • 5-HYDROXY-2-NITROBENZOTRIFLUORIDE
  • 5-Hydroxy-2-nitrobenzotrifluoride~TFM
  • Lamprecide, TFM
CAS:
88-30-2
MF:
C7H4F3NO3
MW:
207.11
EINECS:
201-818-2
Product Categories:
  • C6 to C8
  • Bioactive Small Molecules
  • Aromatic Halides (substituted)
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • Organics
  • Phenol&Thiophenol&Mercaptan
  • N
  • Organic Building Blocks
  • Oxygen Compounds
  • Phenols
Mol File:
88-30-2.mol
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4-NITRO-3-(TRIFLUOROMETHYL)PHENOL Chemical Properties

Melting point:
76-79 °C(lit.)
Boiling point:
135-138 °C0.01 mm Hg(lit.)
Density 
1.554
vapor pressure 
0Pa at 20℃
Flash point:
135-138°C/0.01mm
storage temp. 
-20°C
solubility 
soluble in Methanol
form 
Crystalline Powder
pka
6.07(at 25℃)
color 
Yellow
Water Solubility 
15.05g/L at 20℃
Merck 
14,9253
BRN 
2053698
LogP
2.68 at 23℃
CAS DataBase Reference
88-30-2(CAS DataBase Reference)
EPA Substance Registry System
3-Trifluoromethyl-4-nitrophenol (88-30-2)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-28-36/37/39-45
RIDADR 
2588
WGK Germany 
3
RTECS 
GP3520000
Hazard Note 
Irritant
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29089990
Hazardous Substances Data
88-30-2(Hazardous Substances Data)
Toxicity
LD50 oral in mammal (species unspecified): 500mg/kg

MSDS

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4-NITRO-3-(TRIFLUOROMETHYL)PHENOL Usage And Synthesis

Chemical Properties

yellow crystalline powder

Uses

4-Nitro-3-(trifluoromethyl)phenol is used in preparation of Bicyclic Heteroaryl substituted compounds as PAR4 inhibitors.

Uses

Lamprey killer.

Flammability and Explosibility

Not classified

Purification Methods

Crystallise the nitrophenol from *benzene or from pet ether/*benzene mixture. [Beilstein 6 III 1328.]

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