V-PYRRO/NO
V-PYRRO/NO Basic information
- Product Name:
- V-PYRRO/NO
- Synonyms:
-
- 1-[(ETHENYLOXY)-NNO-AZOXY]-PYRROLIDINE
- V-PYRRO/NO
- PYRRO NONOATE
- O2-VINYL 1-(PYRROLIDIN-1-YL)DIAZEN-1-IUM-1,2-DIOLATE
- O2-VINYL 1-(PYRROLIDIN-1-YL)DIAZEN-1-UIM-1,2-DIOLATE
- 1-[(Ethenyloxy)-NNO-azoxy]-pyrrolidine, O2-Vinyl-1-(pyrrolidin-1-yl)diazen-1-uim-1,2-diolate
- 1-(Ethenyloxy)-3-(2-pyrrolidinyl)-3-(5-pyrrolidinyl)-
- V-PYRRO/NO, 1-[(ethenyloxy)-NNO-azoxy]-pyrrolidine
- CAS:
- 179344-98-0
- MF:
- C6H11N3O2
- MW:
- 157.17
- Product Categories:
-
- Heterocyclic Compounds
- Heterocycles
- Nitric Oxide Reagents
- Mol File:
- 179344-98-0.mol
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V-PYRRO/NO Chemical Properties
- Boiling point:
- 220.2±23.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- Flash point:
- 14 °C
- storage temp.
- −20°C
- solubility
- Ethanol
- form
- Pale yellow oil.
- color
- Pale Yellow
- Stability:
- Store in Freezer (> 1 year at -20°)
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V-PYRRO/NO Usage And Synthesis
Chemical Properties
Pale Yellow Oil
Uses
V-PYRRO/NO is a metabolically activated nitric oxide (NO) donor drug that can be used to selectively target NO delivery to the liver. The compound is metabolized by the liver, and spontaneously decomposes with a half-life of 3 seconds, liberating NO. Infusion of 30nmol/kg of V-PYRRO/NO in rats causes only a slight drop in blood pressure. At concentrations >100ug, V-PYRRO/NO increases hepatocyte viability against TNF-a-induced apoptosis by approximately 2-fold compared to cells not treated with this compound. UV/Vis: lmax: 267nm e: 9,700
V-PYRRO/NOSupplier
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