1-METHYLURACIL Chemical Properties

Melting point:

236-238 °C (lit.)

Boiling point:

234.21°C (rough estimate)

Density 

1.3541 (rough estimate)

refractive index 

1.5090 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

1 M NaOH: soluble50mg/mL, clear, colorless

pka

9.77±0.10(Predicted)

form 

Solid

color 

White

Water Solubility 

20g/L(temperature not stated)

CAS DataBase Reference

615-77-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

40

Safety Statements 

22-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

1-METHYLURACIL Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

1-Methyluracil (cas# 615-77-0) is a compound useful in organic synthesis.

Definition

ChEBI: A pyrimidone that is uracil with a methyl group substituent at position 1.

General Description

1-Methyluracil is of special importance in biochemistry, since uracil attaches ribose in ribonucleic acid (RNA) just precisely at the N1 atom. H-bond complex formation between 1-methyluracil and glycine has been investigated by theoretical calculations and FT-IR spectroscopy in Ar matrices. It forms 1:1 complexes with 9-ethyl-8-bromo-2,6-diaminopurine and the complex structure has been determined by three-dimensional X-ray diffraction methods.

1-METHYLURACIL(615-77-0)Related Product Information

• 6-Methyluracil
• 6-amino-5-formamido-1,3-dimethyluracil
• 1,3-Dimethyluracil
• 5-CHLORO-6-METHYLURACIL
• 5-IODO-1,3-DIMETHYLURACIL
• 5-Methyluridine
• 6-Methyl-5-Nitrouracil 5-Nitro-6-Methyluracil
• 5-Methyl-3-methyluracil
• 5,6-Diamino-1-methyluracil
• 1-[2-DEOXY-BETA-D-RIBOFURANOSYL]-5-METHYLURACIL,1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
• Trifluridine
• 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
• 3-(2-HYDROXY-ETHYL)-6-METHYL-1H-PYRIMIDINE-2,4-DIONE
• 6-(TRIFLUOROMETHYL)URACIL
• DIHYDROTHYMINE
• CLEVUDINE, 1-(2'-DEOXY-2'-FLUORO-β-L-ARABINOFURANOSYL)-5-METHYLURACIL,1-(2'-DEOXY-2'-FLUORO-BETA-L-ARABINOFURANOSYL)-5-METHYLURACIL
• 6-(Chloromethyl)uracil
• Urapidil hydrochloride