(1S, 2R)-2-(Benzyloxymethyl)-1-hydroxy-3-cyclopentene Chemical Properties

Boiling point:

318.9±22.0 °C(Predicted)

Density 

1.112±0.06 g/cm3(Predicted)

storage temp. 

Store at room temperature

solubility 

Chloroform, DCM, Ethyl Acetate

form 

Oil

pka

14.65±0.40(Predicted)

color 

Pale Yellow

optical activity

Consistent with structure

InChI

InChI=1S/C13H16O2/c14-13-8-4-7-12(13)10-15-9-11-5-2-1-3-6-11/h1-7,12-14H,8-10H2/t12-,13+/m1/s1

InChIKey

WACMQXMZXZTKIV-OLZOCXBDSA-N

SMILES

[C@H]1(O)CC=C[C@@H]1COCC1=CC=CC=C1

(1S, 2R)-2-(Benzyloxymethyl)-1-hydroxy-3-cyclopentene Usage And Synthesis

Uses

(1S,2R)-2-((Benzyloxy)methyl)cyclopent-3-enol is an intermediate in the synthesis of Entecavir (E558900), an oral antiviral drug used in the treatment of hepatitis B infection.

(1S, 2R)-2-(Benzyloxymethyl)-1-hydroxy-3-cyclopentene(110567-21-0)Related Product Information

• 2-amino-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one hydrate
• 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydiMethylsilyl)-3-(hydroxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one
• (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
• (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
• 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
• Dess-Martin periodinane
• Entecavir
• 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine
• (1S,3S,4R)-Entecavir
• (1R,3R,4R)-Entecavir
• Entecavir Impurity 17(Entecavir EP Impurity C)
• (1'S,3'S,4'S)-Entecavir IsoMer
• Entecavir Impurity
• 6-O-Benzyl-4-dehydroxy-4-diMethylphenylsilyl Entecavir
• Entecavir Impurity 32
• 2-amino-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one
• Entecavir Impurity 6
• (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(benzyloxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanone