4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties

Melting point:

220 °C

storage temp. 

-20°C Freezer

solubility 

DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml

form 

Powder

color 

Orange

BRN 

3840711

EPA Substance Registry System

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0)

Safety Information

Hazard Codes 

Xn

Risk Statements 

63-36-22

Safety Statements 

36/37/39-26

WGK Germany 

3

HS Code 

29413000

MSDS

• Language:English Provider:ACROS

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

orange powder

Uses

Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.

Uses

An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE(4465-65-0)Related Product Information

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