4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO: 23 mg/mL

form 

solid

color 

brown

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE Usage And Synthesis

Uses

GR 144053 Trihydrochloride is a glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic.

Biological Activity

A potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC 50 = 37 nM). Orally active and highly effective at inhibiting thrombus formation in vivo .

4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE(201304-22-5)Related Product Information

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