ChemicalBook > Product Catalog > Organic Chemistry > Organic fluorine compound > Fluoro phenylacetic series > α,α-Difluorophenylacetic acid
α,α-Difluorophenylacetic acid
α,α-Difluorophenylacetic acid Basic information
- Product Name:
- α,α-Difluorophenylacetic acid
- Synonyms:
-
- DIFLUORO(PHENYL)ACETIC ACID
- 2,2-DIFLUORO-2-PHENYLACETIC ACID
- A,A-DIFLUOROPHENYLACETIC ACID
- ALPHA,ALPHA-DIFLUOROPHENYLACETIC ACID
- alpha-Difluoro-benzeneacetic acid
- ɑ,ɑ-Difluorophenylacetic acid, 99%
- 2,3-DIFLUOROPHENYLACETIC ACID 95+%
- 2,3-DIFLUUOROPHENYL ACETIC ACID
- CAS:
- 360-03-2
- MF:
- C8H6F2O2
- MW:
- 172.13
- EINECS:
- 623-610-4
- Product Categories:
-
- Fluorinated Building Blocks
- Organic Building Blocks
- Aryl Fluorinated Building Blocks
- Building Blocks
- Organic Fluorinated Building Blocks
- Other Fluorinated Organic Building Blocks
- Aromatic compound
- Fluorobenzene
- Miscellaneous
- C8
- C8-C12
- Carbonyl Compounds
- Carboxylic Acids
- Chemical Synthesis
- Mol File:
- 360-03-2.mol
More
Less
α,α-Difluorophenylacetic acid Chemical Properties
- Melting point:
- 65-75 °C
- Boiling point:
- 0°C
- Density
- 1.338±0.06 g/cm3(Predicted)
- Flash point:
- 0°C
- storage temp.
- Refrigerator, Under inert atmosphere
- solubility
- Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
- form
- Solid
- pka
- 1.04±0.10(Predicted)
- color
- White to Pale Yellow
- CAS DataBase Reference
- 360-03-2(CAS DataBase Reference)
More
Less
Safety Information
- Hazard Codes
- C,Xi,Xn
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-36/37-36/37/39
- RIDADR
- UN3261
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 2916399090
More
Less
α,α-Difluorophenylacetic acid Usage And Synthesis
Description
α,α-Difluorophenylacetic acid is a phenylacetic acid with two fluorides on the benzylic carbon. The inductive effect of the difluoromethyl group increases the acidity of α,α-difluorophenylacetic acid. α,α-difluorophenylacetic acid and 2-arylbenzoimidazoles could be used as reaction substrates to synthesise difluoroarymethyl-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-ones through radical cascade cyclization[1].
Chemical Properties
white to light yellow crystal powde
References
[1] Kaixia Sui, Yuting Leng* and Yangjie Wu*. “Synthesis of Difluoroarymethyl-Substituted Benzimidazo[2,1-a]isoquinolin-6(5H)-ones under Mild Conditions.” ACS Omega 8 8 (2023): 7517–7528.
α,α-Difluorophenylacetic acidSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
INTATRADE GmbH
- Tel
- +49 3493/605464
- sales@intatrade.de
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
Wuhan Chemwish Technology Co., Ltd
- Tel
- 86-027-67849912
- sales@chemwish.com
More
Less
α,α-Difluorophenylacetic acid(360-03-2)Related Product Information
- 3,4-Difluorophenylacetic acid 98%,3,4-DIFLUOROPHENYLACETIC ACID
- 2,4-Difluorophenylacetic acid 97%,2,4-DIFLUOROPHENYLACETIC ACID
- à-hydroxy-2,3-difluorophenylacetic acid,alpha-Hydroxy-2,3-difluorophenylacetic acid
- à-hydroxy-2,6-difluorophenylacetic acid,alpha-Hydroxy-2,6-difluorophenylacetic acid
- 2,6-Difluorophenylacetic acid 97%,2,6-DIFLUOROPHENYLACETIC ACID
- 2,3-Difluorophenylacetic acid
- 3,4-DIFLUOROPHENYLACETIC ACID METHYL ESTER
- 3,5-DIFLUOROPHENYLACETIC ACID,3,5-Difluorophenylacetic acid 99%
- A,A-DIFLUOROPHENYLACETIC ACID ETHYL ESTER,DIFLUOROPHENYLACETIC ACID ETHYL ESTER
- 2,5-DIFLUOROPHENYLACETIC ACID,2,5-Difluorophenylacetic acid 97%
- 3-CHLORO-2,4-DIFLUOROPHENYLACETIC ACID
- 3-CHLORO-2,6-DIFLUOROPHENYLACETIC ACID
- alpha-Hydroxy-2,4-difluorophenylacetic acid,à-hydroxy-2,4-difluorophenylacetic acid
- alpha-Hydroxy-3,4-difluorophenylacetic acid,à-hydroxy-3,4-difluorophenylacetic acid
- à-hydroxy-2,5-difluorophenylacetic acid
- 4-CHLORO-2,6-DIFLUOROPHENYLACETIC ACID
- à-hydroxy-3,5-difluorophenylacetic acid,alpha-Hydroxy-3,5-difluorophenylacetic acid
- Phenylacetic acid