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Dehydroandrographolide

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Dehydroandrographolide Basic information

Product Name:
Dehydroandrographolide
Synonyms:
  • ANDROGRAPHOLIDE, DEHYDRO-
  • DEHYDROANDROGRAPHOLIDE
  • 14-Deoxy-11-dehydroandrographolide
  • Dehydroandrographoline
  • 14-(P)
  • DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE
  • (3E)-3-[2-[(1S,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone
  • 2(3H)-Furanone,3-[2-[(1S,4aS,5R,6R,8aS)-decahydro-
CAS:
134418-28-3
MF:
C20H28O4
MW:
332.43
Product Categories:
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
134418-28-3.mol
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Dehydroandrographolide Chemical Properties

Melting point:
205-208oC
Boiling point:
508.0±45.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
Acetic Acid (Very Slightly), DMSO (Slightly), Ethanol (Very Slightly)
form 
Solid
pka
14.84±0.70(Predicted)
color 
White
biological source
plant (Andrographis paniculata)
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Safety Information

Safety Statements 
24/25
HS Code 
29322090
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Dehydroandrographolide Usage And Synthesis

Chemical Properties

White crystalline powder, easily soluble in ethanol, acetone, soluble in chloroform, slightly soluble in benzene, almost insoluble in water, from Andrographis paniculata whole plant.

Uses

Dehydroandrographolide is a natural diterpenoid with activity against HBV (hepatitis B) DNA replication. Hepatoprotective agent.

Biological Activity

Dehydroandrographolide possesses activity against hepatitis B virus DNA replication.

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